Vitamin D deficiency in critically ill patients.

n engl j med 360;18 nejm.org april 30, 2009 1912 sions,2 and we also did not detect aromatase protein in the glandular and stromal compartments of ectopic endometrial tissue. We recently found that what was believed to be aromatase protein was mainly endogenous biotin labeling or iron deposits.3 Using three different protocols, we found only barely detectable amounts of aromatase messenger RNA (mRNA). Among 21 peritoneal endometriotic lesions, 16 were aromatase-negative and 5 were near the limit of detection. Our results suggest that aromatase produced within endometriotic lesions might not be as important in endometriosis as postulated in Bulun’s review.